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Category: Dental Pharmacology

The different types of astringents used in dentistry

Astringents used in Dentistry Astringents act by precipitating proteins in superficial layers of cells and are used to diminish the excretion or exudation of superficial cells. They are also used as local haemostatics and mummifying agents (discussed elsewhere). The different types of astringents used in dentistry are: TANNIC ACID It is vegetable astringent obtained from [...]

February 8, 2013 | 0 Comments More

Contraindications to sedation in Dentistry

Contraindications to sedation in Dentistry Contraindications can be grouped in a similar manner as indications. Psychosocial contraindications Patients must be willing and co-operative. A failure to consent for treatment is an absolute contraindication to the provision of care under sedation. Similarly, patients must co-operate to allow the administration of the sedative agents by a given [...]

December 21, 2012 | 0 Comments More

Indications for sedation in Dentistry

Indications for sedation in Dentistry The indications for sedation can be considered under three main headings: psychosocial, medical and dental. Psychosocial indications Indications relating to anxieties regarding dental treatment include: • phobias — specific: drills, needles, extractions — general: things in mouth, all dental procedures • gagging: inability to tolerate objects intraorally without retching • [...]

December 21, 2012 | 0 Comments More

Antibiotic protocol for prevention of endocarditis from dental procedures

Antibiotic protocol for prevention of endocarditis from dental procedures Local or no anaesthesia Oral amoxicillin 3 g 1 hour before procedure Or if allergic to penicillin or have had more than a single dose in previous month: oral clindamycin 600 mg 1 hour before procedure Or patients who have had endocarditis: amoxicillin and gentamycin, as [...]

November 10, 2012 | 0 Comments More

What is the mechanism of action of the HIV-1 protease inhibitors

What is the mechanism of action of the HIV-1 protease inhibitors ???? The protease inhibitors represent a major advance in the management of HIV disease. Once HIV- 1 enters a cell, viral RNA undergoes reverse transcription to produce double-stranded DNA. The viral DNA is integrated into the host genome. It is then transcribed and translated [...]

August 27, 2011 | 0 Comments More

HIV-1 Protease Inhibitors and Precautions for the Dental Practitioner

HIV-1 Protease Inhibitors and Precautions for the Dental Practitioner Saquinavir (Invirase) ADVERSE REACTION Nausea, diarrhea, abdominal discomfort, and rash INTERACTIONS Avoid drugs that alter the cytochrome P450 activity in the liver because they affect the bioavailability of saquinavir. Ketoconazole inhibits cytochrome P450 and may result in increased plasma levels of saquinavir. Ritonavir (Norvir) ADVERSE REACTION [...]

August 27, 2011 | 0 Comments More
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